Toledo ( tÉ™-LEE-doh) is a city in and the county seat of Lucas County, Ohio, United States. At the 2020 census, it had a population of 270,871, making Toledo the fourth-most populous city in Ohio, after Columbus, Cleveland, and Cincinnati. Toledo is the 85th-most populous city in the United States. It is the principal city of the Toledo metropolitan area, which had 606,240 residents in 2020. Toledo also serves as a major trade center for the Midwest; its port is the fifth-busiest on the Great Lakes. The city was founded in 1833 on the west bank of the Maumee River and originally incorporated as part of the Michigan Territory. It was re-founded in 1837 after the conclusion of the Toledo War, when it was incorporated in Ohio. After the 1845 completion of the Miami and Erie Canal, Toledo grew quickly; it also benefited from its position on the railway line between New York City and Chicago. The first of many glass manufacturers arrived in the 1880s, eventually earning Toledo its nickname as "The Glass City". Downtown Toledo has been subject to major revitalization efforts, including a growing entertainment district. Toledo is home to the University of Toledo.