San Rafael ( SAN rə-FEL; Spanish for "St. Raphael", Spanish pronunciation: [san rafaˈel]) is a city and the county seat of Marin County, California, United States. The city is located in the North Bay region of the San Francisco Bay Area. As of the 2020 U.S. census, the city's population was 61,271, up from 57,713 in 2010. San Rafael was founded by the Spanish in 1817, when Vicente Francisco de Sarría established Mission San Rafael Arcángel, initially as an asistencia (sub-mission). San Rafael Arcángel was upgraded to full mission status in 1822, a month before Alta California declared independence from Spain as part of Mexico. Following the American Conquest of California, the community of San Rafael incorporated as a city in 1874.